Free NAPLEX Sample Questions

See why TrueLearn is a trusted resource for thousands of pharmacy students. At TrueLearn, we understand that it’s all about the content. That’s why we have high-yield pharmacy practice questions written and screened by high-performing pharmacist authors that are updated on a regular basis to ensure our SmartBanks stay up-to-date with exam blueprint changes. Below are a couple free NAPLEX sample questions so you can see what we mean.

Your First Free NAPLEX Sample Question

Determine the daily caloric provision (measured in kilocalories) of the following total-parenteral-nutrition order: 400 mL of D50W; 1,500 mL of 10% amino acids; 500 mL of 20% lipid emulsion.

Note: Answer must be numeric; round the final answer to the nearest whole number.

Answer and Explanation

D50W contains 50 g of dextrose per 100 mL of water:

400 mL x 50 g/100 mL = 50 g x 4 = 200 g of dextrose x 3.4 kcal/g = 680 kcals of dextrose

10% amino acids contains 10 g of protein per 100 mL:

1,500 mL x 10 g/100 mL = 150 g of protein x 4 kcal/g = 600 kcals of protein

500 mL of 20% lipid emulsion contains 2 kcal per mL = 500 mL x 2 kcal/mL = 1,000 kcal 

Each caloric component is then added together (680 + 600 + 1,000) to determine the total caloric value of the admixture (2,280 kcal).

Did you get it right? The correct answer is: 2280

Bottom Line: Determining the total number of calories provided by a total-parenteral-nutrition order involves calculating the calories provided by each nutritional component, converting those values into kilocalories, and adding the kilocalories provided by each component together to obtain a total.

Your Second Free NAPLEX Sample Question

A 19-year-old woman presents to her physician for her annual checkup. A full sexually transmitted disease panel was run that resulted in a fourfold increase in nontreponemal test titers. She is otherwise asymptomatic and was unaware she had been exposed to syphilis. The physician is, therefore, suspecting late latent syphilis. What is the first-line recommendation to treat this infection?

A. Azithromycin 1000 mg PO one time
B. Ceftriaxone 250 mg IM one time
C. Doxycycline 100 mg PO BID for 14 days
D. Penicillin G 2.4 million units IM weekly for 3 doses
E. Valacyclovir 1000 mg PO BID for 7-10 days

Answer and Explanation

Latent syphilis is defined as syphilis characterized by seroreactivity without other evidence of primary, secondary, or tertiary disease. Late latent syphilis is latent syphilis where infection occurred more than 12 months ago or an unknown time period.

The recommended treatment is penicillin G 2.4 million units IM weekly for 3 doses. The recommended regimen for primary syphilis is penicillin G 2.4 million units IM in a single dose.

Did you get it right? The correct answer is: D

Incorrect Answer Explanations

Answer A: Azithromycin 1000 mg PO one time is the first-line regimen for chlamydia.

Answer B: Ceftriaxone 250 mg IM one time is the first-line regimen for gonorrhea.

Answer C: Doxycycline 100 mg PO BID for 14 days is an alternative regimen for many infections, but penicillin is the first-line recommendation.

Answer E: Valacyclovir 1000 mg PO BID for 7-10 days is a regimen for genital herpes.

Bottom Line: Asymptomatic with seroreactivity to syphilis is considered latent syphilis. An unknown time period of exposure is late latent syphilis and is treated with 3 doses of penicillin G.

For more information, see:

Workowski KA, Bolan GA; Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep. 2015;64(RR-03):1-137.

DiPiro. Pharmacotherapy: A Pathophysiologic Approach, 10e. Chapter 117: Sexually Transmitted Diseases.

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